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Updated: May 24, 2026
07:08
Identification of Novel Regulators of Plant Transpiration by Large-Scale Thermal Imaging Screening in Helianthus Annuus
Published on: January 30, 2020
Small molecules present large opportunities in plant biology
Glenn R Hicks1, Natasha V Raikhel
1Center for Plant Cell Biology, Institute for Integrative Genome Biology, Department of Botany and Plant Sciences, University of California, Riverside, CA 92521, USA. ghicks@ucr.edu
Annual Review of Plant Biology
|March 13, 2012
Summary
Chemical genomics in plant biology offers powerful insights into cellular functions and developmental processes. Advances in screening and target identification are driving progress, though challenges in automation and resource accessibility remain.
Area of Science:
- Plant biology
- Chemical genomics
- Molecular mechanisms
Background:
- Chemical genomics has emerged as a significant tool in plant biology research.
- The field has demonstrated its potential for fundamental discoveries by linking cellular function perturbations to plant growth and development.
Purpose of the Study:
- To highlight the advancements and potential of chemical genomics in plant biology.
- To discuss the application of chemical genomics in dissecting complex biological processes and overcoming challenges like functional redundancy.
Main Methods:
- Utilizing small molecules to perturb cellular functions.
- Employing high-content screening and target identification approaches.
- Analyzing growth and developmental phenotypes resulting from chemical treatments.
Main Results:
- Demonstrated success in overcoming functional redundancy in plants.
- Dissected critical molecular pathways, including hormone signaling and intracellular processes.
- Generated new phenotypes through the perturbation of cellular functions.
Conclusions:
- Chemical genomics is a powerful approach for basic plant biology research with untapped potential.
- Ongoing advances in screening and target identification are propelling the field forward.
- Addressing challenges in automation, imaging, analysis, and resource sharing is crucial for future progress.
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