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Updated: May 24, 2026
13:07
Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Current applications of optical coherence tomography for coronary intervention
Giuseppe Ferrante1, Patrizia Presbitero, Robert Whitbourn
1Department of Interventional Cardiology, Istituto Clinico Humanitas IRCCS, Rozzano, Milan, Italy.
International Journal of Cardiology
|March 13, 2012
Summary
Optical coherence tomography (OCT) provides high-resolution coronary imaging, surpassing intravascular ultrasound. This review explores OCT
Area of Science:
- Cardiovascular Imaging
- Medical Technology
- Interventional Cardiology
Background:
- Optical coherence tomography (OCT) is an emerging high-resolution imaging technology for coronary arteries.
- OCT offers approximately 15 μm resolution, significantly higher than intravascular ultrasound.
- Novel OCT systems enable rapid, safe, non-occlusive coronary scanning.
Purpose of the Study:
- To present the physical principles of Fourier domain OCT systems.
- To review clinical and research applications of OCT in interventional cardiology.
- To delineate OCT's role in coronary atherosclerosis assessment and stent implantation analysis.
Main Methods:
- Review of Fourier domain Optical Coherence Tomography principles.
- Analysis of in vivo OCT data for coronary imaging.
- Focus on applications in atherosclerosis and stent evaluation.
Main Results:
- OCT excels in assessing superficial coronary plaque components.
- OCT provides detailed analysis of stent strut coverage and apposition.
- Demonstrates OCT's utility in evaluating vessel wall response to stenting.
Conclusions:
- OCT is a powerful tool for interventional cardiology, offering superior resolution.
- Key applications include coronary atherosclerosis assessment and post-stent analysis.
- Future perspectives and limitations of OCT technology are discussed.
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