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Updated: May 24, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
[Ischemic stroke related to pauci-symptomatic acute aortic dissection. Risks of intravenous thrombolysis]
E Folgoas1, F Toulgoat, M Sévin
1Unité neurovasculaire, service de neurologie, hôpital G-&-R-Laënnec, centre hospitalier et universitaire de Nantes, boulevard Jacques-Monod, 44093 Nantes cedex 1, France. emmanuelle-folgoas@wanadoo.fr
Introduction:
Acute aortic dissection involving the cervical arteries often induces cerebral infarction. In this context, there is a high risk of hemorrhage and thrombolytics are contra-indicated.
Observation:
We report two patients with a cerebral infarction which occurred after a pauci-symptomatic and undiagnosed aortic dissection treated with thrombolysis. The outcome was poor for both patients.
Discussion:
Ischemic strokes related to acute aortic dissection often involve the right carotid artery territory and may manifest without pain. A systematic assessment of supra-aortic arteries might help to identify the underlying diagnosis.
Conclusion:
Acute aortic dissection should be systematically mentioned in the management of the acute ischemic stroke.
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