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Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
[Measles in pregnancy: a review]
M Guillet1, C Vauloup-Fellous, A-G Cordier
1INSERM U764, laboratoire de microbiologie - immunologie biologique, hôpital Antoine-Béclère, AP-HP, université Paris-Sud, Clamart, France.
Measles outbreaks pose risks to all ages, especially young children and adults, including pregnant women. Improved vaccination coverage is crucial for preventing severe complications and congenital measles.
Area of Science:
- Virology
- Epidemiology
- Immunology
Context:
- Measles, a viral disease, can cause severe pneumologic or neurologic issues in children and adults.
- France has experienced a significant measles outbreak since 2008, with over 17,000 cases.
- Pregnant women are particularly affected, facing risks of severe illness, pneumonia, miscarriage, and prematurity.
Purpose:
- To review the latest data on measles virus.
- To provide current vaccine recommendations.
- To suggest management strategies for measles exposure or infection during pregnancy.
Summary:
- Measles incidence decreased with vaccines but outbreaks persist, notably in France since 2008.
- Congenital measles can have dramatic consequences, especially if rash occurs near term.
- Prevention relies on improving immunization coverage to stop virus circulation.
Impact:
- Highlights the importance of vaccination for preventing measles complications.
- Provides guidance for managing measles in pregnant individuals and during outbreaks.
- Emphasizes the need for enhanced public health strategies to control measles transmission.
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