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Related Experiment Video

Updated: May 24, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

Future thinking in Parkinson's disease: an executive function?

Stefania de Vito1, Nadia Gamboz, Maria Antonella Brandimonte

  • 1Human Cognitive Neuroscience, Psychology, University of Edinburgh, Edinburgh, UK. stefaniadv29@libero.it

Neuropsychologia
|March 13, 2012
PubMed
Summary
This summary is machine-generated.

Imagining the future relies on executive control, not just memory. People with Parkinson's disease (PD) show deficits in future thinking linked to executive function, not memory impairment.

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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
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Last Updated: May 24, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Area of Science:

  • Cognitive Neuroscience
  • Neurology

Background:

  • Future thinking was once thought to be solely hippocampus-dependent.
  • Recent neuroimaging suggests frontopolar cortex involvement in future simulation.

Purpose of the Study:

  • To investigate the role of memory versus executive control in future simulation for people with Parkinson's disease (PD).

Main Methods:

  • Thirty-one PD patients and matched controls performed future simulation tasks.
  • Performance was assessed for future episodic details.
  • Patients were evaluated using the Frontal Assessment Battery (FAB) for executive control and memory tests.

Main Results:

  • PD patients generated fewer future episodic details than controls.
  • Patients with the poorest future thinking scores showed deficits in executive control (FAB) but not memory.
  • Future thinking performance correlated with executive control abilities.

Conclusions:

  • Poor future simulation in PD is associated with impaired executive control rather than memory deficits.
  • Flexible retrieval of past details may be essential for envisioning future scenarios.