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Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Pulmonary Edema II: Pathophysiology01:18

Pulmonary Edema II: Pathophysiology

Pulmonary edema is the accumulation of fluid in the interstitial and alveolar spaces of the lungs, impairing gas exchange and oxygen delivery. It may be cardiogenic or noncardiogenic, but both reduce oxygenation and lung compliance.Cardiogenic Pulmonary EdemaCardiogenic edema results from increased hydrostatic pressure in pulmonary capillaries, usually due to left ventricular dysfunction from myocardial infarction, heart failure, or valvular disease. Ineffective cardiac pumping causes blood to...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.

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Updated: May 24, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Acute pulmonary embolism.

Melissa McLenon1

  • 1The University of Texas Health Science Center at Houston School of Nursing, USA.

Critical Care Nursing Quarterly
|March 13, 2012
PubMed
Summary
This summary is machine-generated.

Venous thromboembolism (VTE) is a significant cause of death. This case study explores thrombolytic therapy for acute pulmonary embolism in a cancer patient, highlighting management and outcomes.

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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

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Last Updated: May 24, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
09:22

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

Published on: November 4, 2015

Area of Science:

  • Cardiology
  • Oncology
  • Hematology

Background:

  • Venous thromboembolism (VTE) is a leading cause of cardiovascular death and a significant concern in hospitalized cancer patients.
  • Controversy persists regarding the efficacy and safety of thrombolytic therapy for acute pulmonary embolism (PE), particularly in patients with malignancy.
  • Existing research on thrombolytic therapy for PE has largely excluded patients with active or recent cancer.

Observation:

  • A case of a patient in remission from breast cancer presenting with symptomatic pulmonary emboli is detailed.
  • The patient's presentation, the medical management strategy employed, and the subsequent treatment consequences are described.
  • The case highlights the complexities of managing acute PE in a patient with a history of malignancy.

Findings:

  • Thrombolytic therapy was administered to a cancer patient with symptomatic pulmonary embolism.
  • The presentation, management, and outcomes associated with this treatment approach were observed.
  • The case provides insights into the potential benefits and risks of thrombolysis in this specific patient population.

Implications:

  • This case contributes to the limited literature on thrombolytic therapy for acute pulmonary embolism in cancer patients.
  • It underscores the need for further research to clarify the role of thrombolysis in managing PE in patients with a history of malignancy.
  • Understanding treatment outcomes in such cases can inform clinical decision-making and improve patient care for VTE in oncology settings.