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Cured meat consumption increases risk of readmission in COPD patients
Jordi de Batlle1, Michelle Mendez, Isabelle Romieu
1Centre for Research in Environmental Epidemiology (CREAL), Hospital del Mar Research Institute (IMIM), CIBER Epidemiología y Salud Pública (CIBERESP), and Dept of Experimental and Health Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Abstract:
Recent studies have shown that a high dietary intake of cured meat increases the risk of chronic obstructive pulmonary disease (COPD) development. However, its potential effects on COPD evolution have not been tested. We aimed to assess the association between dietary intake of cured meat and risk of COPD readmission in COPD patients. 274 COPD patients were recruited during their first COPD admission between 2004 and 2006, provided information on dietary intake of cured meat during the previous 2 yrs, and were followed until December 31, 2007 (median follow-up 2.6 yrs). Associations between cured meat intake and COPD admissions were assessed using parametric regression survival-time models. Mean ± SD age was 68 ± 8 yrs, 93% of patients were male, 42% were current smokers, mean post-bronchodilator forced expiratory volume in 1 s (FEV(1)) was 53 ± 16% predicted, and median cured meat intake was 23 g · day(-1). After adjusting for age, FEV(1), and total caloric intake, high cured meat intake (more than median value) increased the risk of COPD readmission (adjusted HR 2.02, 95% CI 1.31-3.12; p=0.001). High cured meat consumption increases the risk of COPD readmission in COPD patients. The assessment of the effectiveness of healthy diet advice should be considered in the future.
Insights
High intake of cured meats significantly increases the risk of readmission for patients with chronic obstructive pulmonary disease (COPD). Dietary changes may be crucial for managing COPD progression.
Area of Science:
- Pulmonary Medicine
- Nutritional Science
- Epidemiology
Background:
- Previous research links high cured meat consumption to increased risk of chronic obstructive pulmonary disease (COPD) development.
- The impact of dietary cured meat intake on the progression and evolution of COPD remains under-investigated.
Purpose of the Study:
- To investigate the association between dietary cured meat consumption and the risk of COPD readmission.
- To evaluate if cured meat intake influences COPD exacerbations requiring hospitalization.
Main Methods:
- A cohort of 274 COPD patients admitted between 2004-2006 provided dietary information on cured meat intake.
- Patients were followed for a median of 2.6 years to track COPD readmissions.
- Parametric regression survival-time models were used to analyze the association, adjusting for age, FEV(1), and caloric intake.
Main Results:
- Patients with high cured meat intake (above the median of 23 g/day) showed a significantly increased risk of COPD readmission.
- The adjusted hazard ratio for readmission among high consumers was 2.02 (95% CI 1.31-3.12; p=0.001).
- Mean patient age was 68 years, 93% were male, and 42% were current smokers.
Conclusions:
- High dietary intake of cured meat is a significant risk factor for COPD readmission in patients with the disease.
- These findings suggest that dietary modification, specifically reducing cured meat consumption, could be a potential strategy for managing COPD.
- Further research should assess the efficacy of dietary advice, including reducing cured meat intake, in clinical practice for COPD management.
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