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Updated: May 24, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
(Z)-3-(1-Benzofuran-2-yl)-2-(3,4,5-tri-meth-oxy-phen-yl)acrylonitrile
Abstract:
In the title compound, C(20)H(17)NO(4), the double bond of the acrylonitrile group separating the 1-benzofuran moiety from the 3,4,5-trimeth-oxy-phenyl ring has Z geometry. The 1-benzofuran groups are π-π stacked with inversion-related counterparts such that the furan ring centroid-centroid distance is 3.804 (5) Å. The dihedral angle between the planes of the trimeth-oxy-phenyl ring and the acrylonitrile group is 24.2 (2)°.
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