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Updated: May 24, 2026

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
5-(4-Eth-oxy-phen-yl)-3-(pyridin-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothio-amide
Abstract:
In the title compound, C(17)H(18)N(4)OS, a pyrazoline derivative, the pyrazoline ring adopts an envelope conformation with the C atom bonded to the benzene ring as the flap atom. The dihedral angle between the pyridine and benzene rings is 80.50 (6)°. The eth-oxy-phenyl group is approximately planar, with an r.m.s. deviation of 0.0238 (1) Å for the nine non-H atoms. In the crystal, mol-ecules are linked by N-H⋯O and N-H⋯S hydrogen bonds into a tape along the b axis. Weak C-H⋯N and C-H⋯π inter-actions are also observed.
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