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Updated: May 24, 2026

Manual Restraint and Common Compound Administration Routes in Mice and Rats
Published on: September 26, 2012
Restraint of undomesticated animals
1Department of Physiology and Biochemistry, University College, Nairobi, Kenya, East Africa.
Abstract:
The capture, by means of chemical immobilization, of about 100 large African animals of 17 different species was accomplished by use of compound M.99, an oripavine with morphine-like activity, but with approximately 1,000 times the activity of morphine. Usually, the compound was used in conjunction with a tranquilizer and scopolamine. The small dose required enabled M.99 to be administered by a projectile syringe of 2-ml. capacity. The effect of the immobilizing compound can be reversed with nalorphine or with compound M.285.
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