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[Cephalic hypersensitivity syndrome]
Toshihiko Shimizu1, Koichi Hirata, Shinya Manaka
1Headache Clinic, Department of Neurosurgery, Institute of Neurology, Tokyo Women's Medical University.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|March 15, 2012
Summary
A new syndrome, "cephalic hypersensitivity syndrome," is identified in patients with chronic headache, dizziness, and ringing in the head. This condition involves underlying cortical hyperexcitability, treatable with triptans to prevent recurrence.
Area of Science:
- Neurology
- Neurophysiology
Context:
- Increasing prevalence of chronic headache with associated dizziness and cephalic ringing.
- Limitations of the trigeminovascular theory in explaining all migraine presentations.
- Emerging evidence implicating cortical hyperexcitability in headache disorders.
Purpose:
- To investigate the underlying pathophysiology of chronic headache accompanied by dizziness and cephalic ringing.
- To define a novel syndrome based on observed clinical presentation and electroencephalographic (EEG) findings.
- To propose a treatment strategy for the newly defined syndrome.
Summary:
- EEG measurements were conducted on 1,000 patients experiencing daily headache, dizziness, and cephalic ringing.
- A new syndrome, "cephalic hypersensitivity syndrome," is proposed, characterized by subliminal cortical hyperexcitability.
- This hyperexcitability manifests as symptoms like dizziness and cephalic ringing, despite being otherwise undetectable.
Impact:
- Introduces "cephalic hypersensitivity syndrome" as a distinct clinical entity.
- Highlights the role of cortical hyperexcitability in specific headache presentations.
- Suggests triptan medication as a targeted treatment to reduce symptom recurrence by attenuating hyperexcitability.
