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Updated: May 24, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
Published on: May 17, 2024
Giant congenital nevus with plexiform neurofibroma and malignant peripheral nerve sheath tumor
Drazen Shejbal1, Vladimir Bedekovic, Hrvoje Cupic
1City Hospital Pakrac, Division of Otorhinolaryngology, Pakrac, Croatia. dr.azen@vip.hr
Abstract:
A female patient with a giant congenital nevus associated with plexiform neurinoma and malignant peripheral nerve sheath tumor (MPNST) on head and neck is presented. We theoretically discuss possibilities of mutual origin all three entities, including the Boland theory of neurochristopaty. The clinical, surgical, and histologic aspects of the disease are discussed. Only one similar case in written literature was described.
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