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Bleeding disorders in obstetrics and gynaecological practice

Mussarat Ashraf1, Zaiba Sher, Nabila Irum

  • 1Department of Obstetrics and Gynaecology, PAEC General Hospital, Islamabad. musseratashraf@yahoo.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|March 15, 2012
PubMed

Insights

This study identified common bleeding disorders in obstetric and gynecologic patients, finding HELLP syndrome and gestational thrombocytopenia most frequent in pregnant women, and Von Willebrand disease in those with menorrhagia.

Area of Science:

  • Obstetrics and Gynecology
  • Hematology

Background:

  • Bleeding disorders pose significant risks in obstetric and gynecologic care.
  • Understanding local prevalence is crucial for effective patient management.

Purpose of the Study:

  • To determine the frequency, types, symptoms, and management of bleeding disorders in local obstetric and gynecologic practice.
  • To identify common bleeding disorders in pregnant patients and those with menorrhagia.

Main Methods:

  • A one-year descriptive study was conducted at Pakistan Atomic Energy Commission General Hospital, Islamabad.
  • Data collected on patient demographics, bleeding disorder types, symptoms, and treatments.

Main Results:

  • HELLP syndrome (27.7%) and gestational thrombocytopenia (22%) were the most frequent bleeding disorders in pregnant patients.
  • Von Willebrand disease (16.66%) was the most common in gynecologic patients with menorrhagia.
  • Other identified disorders included Glanzmann's thrombasthenia, autoimmune hemolytic anemia, post-transfusion purpura, and factor V deficiency.

Conclusions:

  • HELLP syndrome and gestational thrombocytopenia are key considerations in pregnant patients presenting with bleeding.
  • Von Willebrand disease is a significant cause of menorrhagia in gynecologic patients.
  • Comprehensive assessment and management strategies are vital for these conditions.

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