Related Experiment Video
Updated: May 24, 2026

Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats
Published on: July 5, 2024
Hypoperfusion, shock states, and abdominal compartment syndrome (ACS)
Koen Ameloot1, Carl Gillebert, Nele Desie
1Intensive Care Unit, Ziekenhuis Netwerk Antwerpen, Campus Stuivenberg/Erasmus, Antwerpen, Belgium.
Abstract:
Cardiovascular dysfunction and failure are commonly encountered in patients with intra-abdominal hypertension or abdominal compartment syndrome. Accurate assessment and optimization of preload, afterload, and contractility are essential to restoring end-organ perfusion and maximizing patient survival. Application of a goal-directed resuscitation strategy, including abdominal decompression, when indicated, improves cardiac function, reverses end-organ failure, and minimizes intra-abdominal hypertension-related patient morbidity and mortality.
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