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Updated: May 24, 2026

A Novel Surgical Technique in a Sheep Model for Suburethral Graft Implantation
Published on: June 20, 2025
Xenograft iterposition in female urethral diverticulum surgery
Egoitz Tolosa Eizaguirre1, J E Robles Garcia, J Barba Abad
1Urology Department, Clinica Universidad de Navarra.Pamplona, Avenida Pio XII 36, Pamplona, Spain. egoitztolosa@gmail.com
Objective:
To describe the use collagen xenograft as adjuvant therapy in the surgical treatment of female urethral diverticulum (FUD) and to perform a bibliographic review.
Methods:
We performed a surgical approach to remove the diverticulum and repair the remaining dead space with a porcine collagen mesh to avoid fistulas. Monitoring is done by MRI.
Results:
After two years of follow up the patient improved considerably, disappearing the previous symptoms. Follow-up MRI showed no abnormality: There was no inflammatory reaction or encapsulation of any kind.
Conclusions:
We recognize that the flap or the use of a xenograft are not always necessary, but due to its technical simplicity and effectiveness, it is an important tool for diverticulum surgery. However, more experience is needed to assess the appropriateness of this method.
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