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Fragrance material review on 2-hydroxy-2-phenylethyl acetate
D McGinty1, C S Letizia, A M Api
1Research Institute for Fragrance Materials Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA. dmcginty@RIFM.org
This review examines the toxicology and dermatology of 2-hydroxy-2-phenylethyl acetate, a fragrance ingredient. Data supports its safety as part of the aryl alkyl alcohol simple acid esters (AAASAE) group.
Area of Science:
- Toxicology
- Dermatology
- Fragrance Chemistry
Background:
- 2-Hydroxy-2-phenylethyl acetate belongs to the aryl alkyl alcohol simple acid esters (AAASAE) fragrance group.
- AAASAE compounds are synthesized from aryl alkyl alcohols and simple carboxylic acids.
- This review focuses on toxicologic and dermatologic data for this specific ingredient.
Purpose of the Study:
- To present a comprehensive toxicologic and dermatologic review of 2-hydroxy-2-phenylethyl acetate.
- To summarize available scientific literature concerning this fragrance ingredient.
- To provide data supporting the safety assessment of AAASAE fragrance ingredients.
Main Methods:
- Literature review of toxicology and dermatology studies.
- Evaluation and summarization of existing scientific data.
- Inclusion of physical properties data for the ingredient.
Main Results:
- Compilation of available toxicologic and dermatologic data for 2-hydroxy-2-phenylethyl acetate.
- Physical properties of the ingredient were documented.
- Findings contribute to a broader safety assessment of the AAASAE group.
Conclusions:
- 2-Hydroxy-2-phenylethyl acetate has undergone toxicologic and dermatologic review.
- The data supports the safety of this ingredient within its chemical class.
- Refer to Belsito et al. (2012) for a comprehensive safety assessment of AAASAE materials.
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