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Prediction of ADHD to anxiety disorders: an 11-year national insurance data analysis in Taiwan
Yueh-Ming Tai1, Churn-Shiouh Gau, Susan Shur-Fen Gau
11Taipei Medical University, Taipei, Taiwan.
Objective:
To prospectively investigate prediction of ADHD to anxiety disorders (ANXs) in a national sample of Taiwan.
Method:
From the Taiwan National Health Insurance Dataset (1997-2007), we collected 2,385 cases of new diagnoses of ADHD from 1999 to 2003 and 9,540 sex-, age- and index dates of the first diagnosis of ADHD-matched cohort controls without ADHD. The outcome is age of the first diagnosis of ANXs until December 31, 2007.
Results:
More cases of ADHD (17.7%) developed ANXs than did matched controls (1.9%) with a younger age onset (12.7 years vs. 17.9 years) and a shorter "survival time" (1.4 years vs. 5.0 years). Cox models revealed a significant prediction of ADHD to ANXs controlling for other psychiatric comorbidities [Hazard ratio (HR) = 15.83]. The magnitude of such association was greater in males and decreased with older age of first ADHD diagnosis.
Conclusion:
The findings imply that early detection and treatment for ADHD may offset later development of ANXs.
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