Related Experiment Video
Updated: May 24, 2026
Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
[Atopic dermatitis: a modern view of pediatricians and pediatric allergologist]
Insights
Atopic dermatitis in children often progresses to allergic rhinitis and asthma, highlighting a systemic allergic march. Integrated treatment addressing triggers, diet, and systemic therapies is crucial for managing this condition.
Area of Science:
- Pediatric Allergy and Immunology
- Dermatology
- Immunology
Context:
- Atopic dermatitis (AD) is a prevalent condition in children.
- Understanding the progression of atopic diseases is essential for effective management.
- The concept of the allergic march provides a framework for studying atopy.
Purpose:
- To present a pediatric allergologist's perspective on atopic dermatitis in children.
- To elucidate the concept of the allergic march in pediatric atopy.
- To emphasize the systemic nature of atopic diseases and the importance of integrated treatment.
Summary:
- Atopic dermatitis is viewed as the initial stage of a systemic "allergic march" in children with atopy.
- This progression commonly leads to allergic rhinitis and bronchial asthma, indicating shared immunopathological mechanisms.
- Effective management requires a combined therapeutic approach, including topical corticosteroids, trigger avoidance, dietary adjustments, and long-term systemic H1-antihistamine therapy.
Impact:
- Highlights the interconnectedness of atopic diseases, suggesting potential for unified prevention strategies.
- Underscores the importance of a holistic and systemic approach to managing pediatric atopic dermatitis.
- Provides insights into the long-term management of atopic conditions in children, emphasizing combination therapy.
Abstract:
The article presents the views of pediatric allergologist on the problem of atopic dermatitis/ atopic eczema in children. Atopic dermatitis (AD) is considered from a modern viewpoint of allergic 'march', which is characteristic (typical) for children with atopy. These data indicate to systemic nature of atopic 'march', the first step of which is atopic eczema. Further evolution of atopic dermatitis leads to a transformation of it in other atopic diseases--allergic rhinitis and bronchial asthma; this fact indicates that immunopathological disorders are united in these diseases and it conditions the possibility of prevention. It has taken into consideration the systemic nature of atopic diseases, combined therapy is great important and has to include not only basic local therapy, in particular topical corticosteroids (mometasone furoate--Elokom) during the exacerbation, and the systematic elimination of trigger factors, diet, the removal of the digestive system dysfunctions and the imbalance of vitamins. A long-time systemic basic therapy by H1-antihistamines of second generation, such as desloratadine (Aerius) takes a special place in the treatment of atopic dermatitis.
Related Concept Videos
01:20Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
01:28Asthma I: Introduction
01:30Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
01:26Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
01:30Allergic Reactions: Anaphylaxis
02:06Allergic Reactions