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Low dose intravenous urography: results and technique modifications
R J Keenan1, A List, C Kengsakul
1Department of Radiology, Auckland Hospital, New Zealand.
Australasian Radiology
|May 1, 1990
Summary
Low doses of Iohexol (Omnipaque 350mgl/ml) for intravenous urography reduced contrast by 42% while maintaining diagnostic quality. Technique modifications, like delayed imaging, were needed, suggesting further reductions are possible in older patients.
Area of Science:
- Radiology
- Medical Imaging
- Contrast Media
Background:
- Intravenous urography is a standard diagnostic procedure.
- Optimizing contrast medium dosage is crucial for patient safety and cost-effectiveness.
- Iohexol is a low osmolar contrast agent used in urography.
Purpose of the Study:
- To evaluate the efficacy of reduced doses of Iohexol for intravenous urography.
- To determine if lower contrast volumes impact diagnostic image quality.
- To explore potential for further dose reduction in specific patient demographics.
Main Methods:
- 100 patients undergoing intravenous urography received low doses of Iohexol (Omnipaque 350mgl/ml).
- Dosage was individualized based on age, sex, body weight, and renal function.
- Results were compared to a control group receiving standard contrast doses.
Main Results:
- A 42% reduction in contrast medium was achieved while maintaining diagnostic study quality.
- Nephrographic quality was reduced in the low-dose group, necessitating technique modifications.
- Delayed film sequences were required to optimize imaging in the low-dose group.
Conclusions:
- Reduced doses of Iohexol are effective for intravenous urography.
- Technique adjustments are necessary to compensate for lower contrast volumes.
- Further contrast dose reductions may be feasible, particularly in patients over 40.