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Updated: May 24, 2026
03:19
Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
Published on: June 21, 2024
Bladder diverticulum: clinicopathologic spectrum in pediatric patients.
Riley E Alexander1, Jennifer B Kum, Muhammad Idrees
1Indiana University School of Medicine, Department of Pathology and Laboratory Medicine, Indianapolis, IN, USA. realexan@iupui.edu
Summary
Pediatric bladder diverticula often present with vesicoureteral reflux and urinary tract infections. Malignancy is not associated with these findings in children, unlike in adults.
Area of Science:
- Pediatric Urology
- Congenital Abnormalities
- Oncology
Background:
- Urinary bladder diverticula are rare in children and adults.
- In adults, bladder diverticula are linked to urothelial carcinoma.
- Limited data exists on pediatric bladder diverticula characteristics and associated risks.
Purpose of the Study:
- Analyze a pediatric cohort with bladder diverticula.
- Identify clinical symptoms, congenital syndromes, and treatment methods.
- Investigate the risk of malignant transformation in pediatric bladder diverticula.
Main Methods:
- Retrospective review of 47 pediatric patients (0-19 years) with 60 bladder diverticula (1990-2011).
- Analysis of clinical records and histologic slides.
- Statistical analysis of findings.
Main Results:
- Common findings: vesicoureteral reflux (68%), recurrent UTIs (55%), hydronephrosis (40%).
- 30% of patients had associated congenital syndromes/malformations.
- No cases of malignancy or dysplasia were found in pediatric bladder diverticula.
Conclusions:
- Pediatric bladder diverticula are associated with significant clinical symptoms and urinary tract abnormalities, aiding early detection.
- Congenital syndromes are frequently observed in pediatric patients with bladder diverticula.
- Malignant transformation is extremely rare in pediatric bladder diverticula.
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