Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chicken anemia agent: an electron microscopic study.

M S McNulty1, W L Curran, D Todd

  • 1Veterinary Research Laboratories, Stormont, Belfast, Northern Ireland.

Avian Diseases
|July 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Single radio frequency bucket injection in the 88-Inch Cyclotron using a pulsed high voltage chopper.

The Review of scientific instruments·2024
Same author

The potential of live attenuated vaccines against Cutaneous Leishmaniasis.

Experimental parasitology·2020
Same author

Development of an indirect enzyme-linked immunosorbent assay test for detecting antibodies to chicken astrovirus in chicken sera.

Avian pathology : journal of the W.V.P.A·2015
Same author

A mode converter to generate a Gaussian-like mode for injection into the VENUS electron cyclotron resonance ion source.

The Review of scientific instruments·2014
Same author

Production of high intensity 48Ca for the 88-Inch Cyclotron and other updates.

The Review of scientific instruments·2014
Same author

Chicken astrovirus capsid proteins produced by recombinant baculoviruses: potential use for diagnosis and vaccination.

Avian pathology : journal of the W.V.P.A·2013

Chicken anemia virus (CAV) particles are 26.5 nm and have an icosahedral capsid structure. CAV-specific inclusions and microtubules were observed in infected cells and lymphocytes.

Area of Science:

  • Virology
  • Cell Biology
  • Immunology

Background:

  • Chicken anemia virus (CAA) is a significant pathogen in poultry.
  • Understanding the structure and cellular effects of CAA is crucial for disease control.

Purpose of the Study:

  • To characterize the physical structure of CAA particles.
  • To identify CAA-specific structures within infected host cells and tissues.

Main Methods:

  • Negative staining and electron microscopy were used to analyze CAA particle morphology.
  • Immunoelectron microscopy with monoclonal antibodies identified CAA in infected cells and tissues.

Main Results:

  • CAA particles are 26.5 nm in diameter with an icosahedral capsid (T=3).

Related Experiment Videos

  • Electron-dense nuclear inclusions and cytoplasmic microtubules were observed in infected cells.
  • Virus-like particles were found in the nuclei of infected MDCC-MSB1 cells.

    • Conclusions:

    • CAA exhibits a distinct structure and induces characteristic cellular changes.
    • The absence of nucleolar involvement differentiates CAA from other parvoviruses.