Jove
Visualize
Contact Us

Related Concept Videos

Osmoregulation in Fishes02:32

Osmoregulation in Fishes

53.2K
When cells are placed in a hypotonic (low-salt) fluid, they can swell and burst. Meanwhile, cells in a hypertonic solution—with a higher salt concentration—can shrivel and die. How do fish cells avoid these gruesome fates in hypotonic freshwater or hypertonic seawater environments?
53.2K
FISH - Fluorescent In-situ Hybridization02:07

FISH - Fluorescent In-situ Hybridization

24.6K
Fluorescence in situ hybridization, or FISH, was developed in the early 1980s and has quickly become one of the most widely used techniques in cytogenetics. Labeled probes are used to bind complementary DNA or RNA sequences on a chromosome or in a region within a cell. Earlier, the probes could only be obtained by cloning or reverse transcription of a DNA template. Currently, the probe oligonucleotides can be synthesized synthetically. Additionally, with the advancement of optical techniques,...
24.6K
Electron Transport Chains01:28

Electron Transport Chains

113.1K
The final stage of cellular respiration is oxidative phosphorylation that consists of two steps: the electron transport chain and chemiosmosis. The electron transport chain is a set of proteins found in the inner mitochondrial membrane in eukaryotic cells. Its primary function is to establish a proton gradient that can be used during chemiosmosis to produce ATP and generate electron carriers, such as NAD+ and FAD, that are used in glycolysis and the citric acid cycle.
The ETC is comprised of...
113.1K
Photosystem I01:27

Photosystem I

70.1K
Although structurally similar to photosystem II (PSII), photosystem I (PSI) is has a different electron supplier and electron acceptor.
Both these photosystems work in concert. An excited electron from PSII is relayed to PSI via an electron transport chain in the thylakoid membrane of the chloroplast, which is comprised of the carrier molecule plastoquinone, the dual-protein cytochrome complex, and plastocyanin. As electrons move between PSII and PSI, they lose energy and must be re-energized...
70.1K
Convergent Evolution01:54

Convergent Evolution

33.1K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
33.1K
What is Biodiversity?01:19

What is Biodiversity?

33.9K
Biodiversity describes the variety of living things at multiple organizational levels: genetic, species and ecosystem diversity. Species diversity includes all branches of the evolutionary tree from single-celled prokaryotic organisms, bacteria, and archaea, to the eukaryotic kingdoms: plants; animals; fungi; and protists. To date, there have been about 1.75 million species identified, and new species are discovered every week.
33.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Elephant alcohol dehydrogenase and aldehyde dehydrogenase: Genomic, transcriptomic, and enzymatic analyses raise questions about anecdotal inebriation.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP·2026
Same author

Integrated genomic, transcriptomic, and microsomal metabolic profiling of Cytochrome P450s in squirrels.

The Journal of veterinary medical science·2026
Same author

Evaluation of lead exposure's link to autism-like behaviours and Shank 3 gene expression in C57BL/6J mice.

The Journal of veterinary medical science·2026
Same author

Maternal blood lead levels and proximity to legacy mining contamination in Kabwe, Zambia: socioeconomic disparities and potential implications on fetal health.

Environmental science and pollution research international·2026
Same author

Corrigendum to "Intergenerational sex-specific transcriptomic alterations in gonads of mice after parental lead exposure" [Reprod. Toxicol. 140 (2026) 109154].

Reproductive toxicology (Elmsford, N.Y.)·2026
Same author

Micro- and mesoplastic contaminants in marine diving ducks: A first assessments from the coast of Japan.

Marine pollution bulletin·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Feb 12, 2026

Necropsy-based Wild Fish Health Assessment
07:57

Necropsy-based Wild Fish Health Assessment

Published on: September 11, 2018

18.1K

Cytochrome P450 (CYP) in fish.

Tomohide Uno1, Mayumi Ishizuka, Takao Itakura

  • 1Laboratory of Biological Chemistry, Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University, Nada-ku Hyogo, Japan. unotom@kobe-u.ac.jp

Environmental Toxicology and Pharmacology
|March 16, 2012
PubMed
Summary

This review details Cytochrome P450 (CYP) gene families in fish, identifying 137 genes across 18 families. It highlights eight key CYP families and their role in environmental stress responses.

More Related Videos

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
07:38

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

10.7K
Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c
07:42

Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c

Published on: June 29, 2011

17.9K

Related Experiment Videos

Last Updated: Feb 12, 2026

Necropsy-based Wild Fish Health Assessment
07:57

Necropsy-based Wild Fish Health Assessment

Published on: September 11, 2018

18.1K
A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
07:38

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s

Published on: September 25, 2017

10.7K
Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c
07:42

Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c

Published on: June 29, 2011

17.9K

Area of Science:

  • Biochemistry and Molecular Biology
  • Environmental Toxicology
  • Aquatic Genomics

Background:

  • Cytochrome P450 (CYP) enzymes are crucial hemoproteins involved in metabolizing diverse compounds in many organisms.
  • Fish CYP gene research has expanded significantly, with 137 identified genes across 18 families in various fish species.
  • Japanese pufferfish (Takifugu rubripes) alone possess 54 identified CYP genes.

Purpose of the Study:

  • To provide a comprehensive overview of Cytochrome P450 (CYP) gene families identified in fish.
  • To focus on eight prominent CYP families (CYP1, CYP2, CYP3, CYP4, CYP11, CYP17, CYP19, CYP26) extensively studied in fish.
  • To explore the insights gained into the regulation of fish P450 genes in response to environmental stressors like water pollution.

Main Methods:

  • Literature review and synthesis of existing research on fish Cytochrome P450 genes.
  • Classification and cataloging of identified CYP genes across different fish species.
  • Analysis of studies focusing on the functional roles and regulatory mechanisms of specific CYP families in fish.

Main Results:

  • Identification of 137 Cytochrome P450 genes in fish, categorized into 18 distinct families.
  • Detailed examination of eight key CYP families (CYP1, CYP2, CYP3, CYP4, CYP11, CYP17, CYP19, CYP26) due to their significant research focus.
  • Evidence showing that fish CYP genes are regulated by environmental factors, particularly water pollution.

Conclusions:

  • Fish possess a diverse array of Cytochrome P450 gene families, reflecting their importance in detoxification and metabolic processes.
  • The studied CYP families play critical roles in fish adaptation and response to environmental challenges.
  • Further research into fish CYP genes is vital for understanding aquatic ecosystem health and the impacts of pollution.