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Updated: May 24, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
[Skin and soft tissue infections]
1Medizinische Klinik, Kantonsspital Olten. jpiso_ol@spital.ktso.ch
Abstract:
Skin- and Soft tissue infections are a frequent problem in hospital as well as in ambulatory care. Diagnostic procedures and treatment principles have to include the most frequent pathogens. While the acute forms of skin and soft tissue infections, with, necrotising fasciitis as important exception, rarely cause diagnostic or therapeutic problem, the treatment of patients with recurrent furunculosis, chronic wounds and diabetic feet is often difficult and frustration for patients and physicians. This article gives an overview of the most important problems and treatment strategies.
Insights
Skin and soft tissue infections (SSTIs) are common. This review covers frequent pathogens, diagnostic approaches, and treatment strategies for challenging cases like recurrent infections and diabetic foot ulcers.
Area of Science:
- Infectious Diseases
- Dermatology
- Microbiology
Context:
- Skin and soft tissue infections (SSTIs) represent a significant clinical challenge in both hospital and outpatient settings.
- Effective management necessitates understanding prevalent pathogens and tailored diagnostic and therapeutic strategies.
- Acute SSTIs are generally manageable, but chronic or recurrent forms pose considerable difficulties.
Purpose:
- To provide a comprehensive overview of common pathogens implicated in SSTIs.
- To outline current diagnostic procedures and treatment principles for SSTIs.
- To address the complexities in managing challenging SSTI cases, including recurrent furunculosis, chronic wounds, and diabetic foot infections.
Summary:
- SSTIs are frequent, requiring focus on common causative agents.
- Acute infections are typically straightforward, unlike chronic conditions.
- Recurrent furunculosis, chronic wounds, and diabetic foot infections present significant management challenges.
Impact:
- Improved understanding of SSTI pathogens and management.
- Enhanced treatment strategies for difficult-to-treat SSTIs.
- Better patient outcomes and reduced physician frustration in managing chronic SSTIs.
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