Related Experiment Video
Updated: May 24, 2026

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography
Published on: April 28, 2020
Imposing respiratory variability patterns
Elke Vlemincx1, Ilse Van Diest, Omer Van den Bergh
1Department of Psychology, Research Group on Health Psychology, University of Leuven, Leuven, Belgium. elke.vlemincx@ppw.kuleuven.be
Abstract:
To ensure respiratory stability and flexibility, healthy breathing shows balanced variability consisting of considerable correlated variability (parameters of each breath are correlated to parameters of adjoining breaths) and some random variability. Sighing resets this balance when respiration lacks variability or becomes excessively irregular. The present study aimed to investigate the effect of imposed patterns of breathing variability on sighing and self-reported (dis)comfort. Spontaneous breathing was compared to imposed non-variable, correlated and random breathing. Results show that executing imposed breathing is difficult, demanding, and induces tension. Sigh occurrence following spontaneous and imposed breathing patterns could be predicted by self-reported discomfort and increased random variability. However, including non-variable, correlated and random breathing patterns only, the effects of self-reported discomfort on sigh occurrence override the effects of altered breathing variability.
Related Concept Videos
Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Alterations in Respiration II
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes include...
Respiratory Volumes and Capacities I
Physical Assessment of the Respiratory Tract II: Inspection
Chest Configuration
The chest configuration can...
Respiratory Volumes
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Respiratory Capacities
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...

