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The interactions between hemostasis and resistance training: a review
Dahan da Cunha Nascimento1, Frederico Ribeiro Neto, Frederico Santos de Santana
1Physical Education Department, UNIEURO University Center, Brasília, DF, Brazil.
Resistance training improves blood clotting factors, particularly fibrinolysis, in healthy adults and those with coronary artery disease. High-volume training enhances fibrinolytic response, while high-intensity training increases platelet activity.
Area of Science:
- Exercise physiology
- Cardiovascular health
- Hemostasis
Background:
- Physical inactivity is a risk factor for cardiovascular disease and arterial changes.
- Regular exercise, including resistance training, aids in coronary artery disease prevention.
- Resistance training can positively influence hemostatic parameters, leading to a less thrombotic blood profile.
Purpose of the Study:
- To review studies, mechanisms, and outcomes of resistance training's effectiveness on hemostasis.
- To analyze the impact of different resistance training protocols on hemostatic markers.
- To assess the acute effects of resistance training on hemostasis in individuals with coronary artery disease.
Main Methods:
- Systematic literature search of Pubmed, Scopus, Medline, Scielo, Lilacs, Ibecs, and Cochrane databases.
- Inclusion of seventeen studies after an initial search and exclusion of ten articles.
- Analysis of training protocols focusing on volume, intensity (e.g., % of 1 maximum repetition), and participant characteristics.
Main Results:
- High-volume resistance training protocols in young adults demonstrated a greater fibrinolytic response.
- Resistance training protocols with intensities exceeding 80% of 1 maximum repetition were associated with increased platelet activity.
- A single session of resistance training in subjects with coronary artery disease improved the fibrinolytic system (tissue plasminogen activator) without increasing thrombotic markers.
Conclusions:
- Resistance training effectively modulates hemostasis, with varying responses based on training volume and intensity.
- Even a single session of resistance training can yield beneficial acute effects on the fibrinolytic system in cardiovascular disease patients.
- Resistance exercise represents a viable strategy for improving hemostatic function and potentially reducing thrombotic risk.
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