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Updated: May 24, 2026

A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
Published on: February 14, 2021
[Pathobiomechanical impairments of the vertebral column in intervertebral disk protrusion and herniation]
Abstract:
Magnetic resonance imaging of patients with intervertebral disk herniation was used to study the stages of degenerative and dystrophic processes in the spinal structures in the presence of intervertebral disk protrusion and herniation. Differences were found in the pathobiomechanical mechanisms in the spinal motor segments of herniation and protrusion in the area of their localization and in the adjacent spinal motor segments. Among the symptoms traditionally analyzed, joint facet joint arthritis and arthrosoarthritis classified as spondyloarthritis by radiodiagnosis were examined for their impact on the rate of herniation and protrusion.
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