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Published on: August 29, 2025
Evaluation of cardiac manifestations in pediatric liver transplant candidates
Nitin Madan1, Ronen Arnon, Rica Arnon
1Division of Pediatric Cardiology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY 10029-6574, USA. rica.arnon@mssm.edu
Insights
Cardiovascular complications in pediatric liver transplant candidates are poorly understood, necessitating better cardiac screening. This review explores cardiac issues and evaluation methods for these children.
Area of Science:
- Pediatric Cardiology
- Hepatology
- Transplant Medicine
Background:
- Limited understanding of cardiovascular involvement in children awaiting liver transplant.
- Absence of established guidelines for cardiac disease evaluation in this population.
Purpose of the Study:
- To review cardiovascular manifestations of pediatric liver disease.
- To discuss applicable testing for cardiac screening in pediatric liver transplant candidates.
Main Methods:
- Literature review of cardiovascular manifestations in pediatric liver disease.
- Analysis of current cardiac testing modalities and their suitability for screening.
Main Results:
- Liver disease presents with diverse cardiovascular changes in children.
- Existing cardiac tests show varying applicability for screening this group.
Conclusions:
- Further research is needed to establish specific cardiac evaluation protocols.
- Standardized screening is crucial for improving outcomes in pediatric liver transplant candidates.
Abstract:
Knowledge concerning the involvement of the cardiovascular system in children awaiting liver transplant is limited. Therefore, no guidelines have been established on evaluating this group of patients for cardiac disease. This review examines the diverse cardiovascular manifestations of liver disease in children. We also discuss the available testing and its applicability in screening for cardiac disease in this vulnerable population.
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