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Related Experiment Video

Updated: May 24, 2026

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

Hydrogels for protein delivery in tissue engineering.

Roberta Censi1, Piera Di Martino, Tina Vermonden

  • 1School of Pharmacy, University of Camerino, via S. Agostino 1, 62032, Camerino (MC), Italy. roberta.censi@unicam.it

Journal of Controlled Release : Official Journal of the Controlled Release Society
|March 17, 2012
PubMed
Summary

Hydrogel technologies are crucial for controlled release of bioactive proteins in tissue engineering. This review explores hydrogel strategies for effective delivery of therapeutic molecules to promote tissue repair.

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Drug Delivery Systems

Background:

  • Tissue defects from disease or trauma pose significant challenges in regenerative medicine.
  • Tissue engineering strategies combine biodegradable scaffolds, cells, and environmental cues like growth factors.
  • Sustainable release of these protein factors from scaffolds is essential for effective tissue repair.

Purpose of the Study:

  • To review hydrogel technologies for controlled release of bioactive molecules in tissue engineering.
  • To discuss protein drug relevance, release mechanisms, and encapsulation methods within hydrogels.
  • To overview hydrogel biomaterials for in vitro and in vivo applications in regenerative medicine.

Main Methods:

  • Literature review of hydrogel technologies for controlled release of proteins.

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Last Updated: May 24, 2026

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Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications
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  • Analysis of encapsulation and immobilization techniques for bioactive molecules in hydrogels.
  • Overview of hydrogel-forming biomaterials used in tissue engineering.

    • Main Results:

    • Hydrogels offer versatile platforms for sustained release of essential proteins.
    • Various hydrogel systems and methods exist for encapsulating and immobilizing bioactive factors.
    • Current hydrogel technologies show promise for in vitro and in vivo tissue engineering applications.

    Conclusions:

    • Hydrogel-based delivery systems are vital for advancing regenerative medicine.
    • Continued research into hydrogel properties and bioactive molecule interactions will enhance tissue repair strategies.
    • Future directions include clinical translation of advanced hydrogel-based therapies.