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Updated: May 24, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
Association of body mass index with exercise cardiopulmonary responses in lung function-matched patients with chronic
Chou-Chin Lan1, Chiu-Ping Su, Lih-Lih Chou
1Division of Pulmonary Medicine, Buddhist Tzu-Chi General Hospital, Taipei Branch, Xindian City, Taipei, Taiwan, Republic of China.
Background And Objectives:
Lung function is traditionally used to define the severity of chronic obstructive pulmonary disease (COPD). However, this does not exclude other factors. This study investigated the influence of body mass index (BMI) on exercise responses and quality of life in patients with COPD matched for values of forced expiratory volume in 1 second (FEV(1)).
Methods:
Underweight, normal-weight, and overweight patients with COPD, matched for FEV(1), were studied. All patients were evaluated by spirometry, a cardiopulmonary exercise test, respiratory muscle strength, and, St. George's Respiratory Questionnaire (SGRQ).
Results:
The baseline characteristics and mean FEV(1) of the 3 groups were similar (P > .05). Respiratory muscle strengths and SGRQ scores were lowest in underweight patients (P < .05). In terms of exercise response, the lowest oxygen uptake at anaerobic threshold and peak exercise, the highest ventilatory equivalent, and the lowest oxygen pulse were evident in underweight patients (P < .05).
Conclusions:
Underweight patients with COPD had lower respiratory muscle strength, impaired exercise capacity, earlier anaerobic metabolism, ineffective ventilation, and poorer quality of life.
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