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Published on: October 30, 2018
Fragrance material review on 2-phenylpropyl acetate
D McGinty1, C S Letizia, A M Api
1Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA. dmcginty@RIFM.org
Summary
This review summarizes toxicologic and dermatologic data for 2-phenylpropyl acetate, a fragrance ingredient. Safety assessments indicate its safe use within the Aryl Alkyl Alcohol Simple Acid Esters (AAASAE) group.
Area of Science:
- Toxicology
- Dermatology
- Fragrance Chemistry
Background:
- 2-Phenylpropyl acetate belongs to the Aryl Alkyl Alcohol Simple Acid Esters (AAASAE) fragrance group.
- AAASAE compounds are synthesized from aryl alkyl alcohols and simple carboxylic acids.
- This review focuses on the toxicologic and dermatologic profile of 2-phenylpropyl acetate.
Purpose of the Study:
- To present a comprehensive review of available toxicologic and dermatologic data for 2-phenylpropyl acetate.
- To evaluate and summarize data on physical properties, acute toxicity, skin and eye irritation, and skin sensitization.
- To contribute to the overall safety assessment of AAASAE fragrance ingredients.
Main Methods:
- Literature review of existing toxicology and dermatology studies.
- Evaluation of data pertaining to physical properties.
- Analysis of acute toxicity, irritation, and sensitization data.
Main Results:
- Summarized physical properties of 2-phenylpropyl acetate.
- Detailed findings on acute toxicity.
- Data on skin irritation, eye irritation, and skin sensitization potential.
Conclusions:
- 2-Phenylpropyl acetate data has been evaluated and summarized.
- The safety assessment of the broader AAASAE group is published concurrently.
- Refer to Belsito et al. (2012) for comprehensive safety assessment of AAASAE materials.
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