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Familial atrophia maculosa varioliformis cutis: first case report from the Indian subcontinent with pedigree analysis
Tarang Goyal1, Anupam Varshney, S K Bakshi
1Department of Dermatology, Venereology and Leprology, Muzaffarnagar Medical College, Muzaffarnagar, India. tarang_derma@yahoo.co.in
Abstract:
Familial atrophia maculosa varioliformis cutis is a very rare disorder with less than 28 cases being reported in the literature worldwide and remains a mystery both as far as genetics and the virtue of its pathogenesis is concerned. We present a case of mother and son, both having this disorder with presentations unique in terms of sites involved and try to draw a five generations pedigree chart for the same. We further support its inheritance pattern as autosomal dominant. Also, we propose oral isotretinoin as an effective treatment modality for the same.
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