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Updated: May 24, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Candidal mediastinitis successfully treated using vacuum-assisted closure following open-heart surgery
Hiroaki Osada1, Hiroyuki Nakajima, Manabu Morishima
1Department of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, Kyoto, Japan. osahiro@kuhp.kyoto-u.ac.jp
Abstract:
Deep sternal wound infections (DSWIs) are an uncommon but serious complication after open-heart surgery. The reported incidence of DSWIs due to Candida albicans is 0.4%, but these infections have an extremely high mortality of 56%. We herein report a rare case of a 79-year old woman who suffered from Candidal DSWI after repeated open-heart surgeries. We treated her with negative pressure wound therapy (NPWT). This is the rare case report that provides evidence that NPWT is a safe and suitable technique for the management of Candidal DSWIs.
Insights
Deep sternal wound infections (DSWIs) are a rare but severe complication after open-heart surgery. This case report shows negative pressure wound therapy (NPWT) is a safe and effective treatment for Candida albicans DSWIs.
Area of Science:
- Cardiology
- Infectious Diseases
- Wound Care
Background:
- Deep sternal wound infections (DSWIs) are a serious complication following open-heart surgery.
- Candida albicans is a rare but highly fatal cause of DSWIs, with a 56% mortality rate.
Observation:
- A 79-year-old woman developed a Candidal DSWI after multiple open-heart surgeries.
- The patient's infection was successfully managed using negative pressure wound therapy (NPWT).
Findings:
- This case demonstrates the successful application of NPWT in treating a rare Candidal DSWI.
- NPWT proved to be a safe and suitable method for managing this severe post-surgical infection.
Implications:
- Negative pressure wound therapy (NPWT) offers a viable treatment option for challenging Candidal DSWIs.
- This case highlights the importance of considering NPWT for complex sternal wound infections, even those caused by fungi.
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