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Published on: April 19, 2019
Fifty years of oxacalix[3]arenes: A review
Kevin Cottet1, Paula M Marcos, Peter J Cragg
1School of Pharmacy and Biomolecular Sciences, Huxley Building, University of Brighton, Brighton BN2 4GJ, UK.
Abstract:
Hexahomotrioxacalix[3]arenes, commonly called oxacalix[3]arenes, were first reported in 1962. Since then, their chemistry has been expanded to include numerous derivatives and complexes. This review describes the syntheses of the parent compounds, their derivatives, and their complexation behaviour towards cations. Extraction data are presented, as are crystal structures of the macrocycles and their complexes with guest species. Applications in fields as diverse as ion selective electrode modifiers, fluorescence sensors, fullerene separations and biomimetic chemistry are described.
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