Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hand hygiene

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...

Staphylococcal Skin Infections

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

The Skin Microbiota

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...

Surface Membrane Barriers

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...

Development of Immunocompetence

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Radiometer calibration using machine learning.

Scientific reports·2025

Same author

Exploring preterm birth and low birth weight as environmental sensitivity factors: A scoping review of socio-emotional and cognitive developmental outcomes.

Neuroscience and biobehavioral reviews·2025

Same author

Receiver design for the REACH global 21-cm signal experiment.

Experimental astronomy·2025

Same author

The role of individual differences in environmental sensitivity in teachers' stress and burnout at work.

Stress and health : journal of the International Society for the Investigation of Stress·2024

Same author

The Impact of Oxidative Stress on Pregnancy. The Neglected Role of Alcohol Misuse.

La Clinica terapeutica·2024

Same author

Human semen quality and environmental and occupational exposure to pollutants: A systematic review.

Annali di igiene : medicina preventiva e di comunita·2023

Search research articles

Related Experiment Video

Updated: May 24, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

[Skin antisepsis in premature infants].

G Agolini¹, G Faldella, E Janes

¹Dip Scienze Biomediche, Farmacologia, Az. Universitaria, Trieste.

La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics

|March 20, 2012

Summary

Effective antiseptics are crucial for preventing infections in premature infants receiving total parenteral nutrition. This study reviews biocides like sodium hypochlorite and chlorhexidine for optimal skin tolerability and efficacy.

More Related Videos

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics

Published on: September 16, 2022

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Related Experiment Videos

Last Updated: May 24, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics

Published on: September 16, 2022

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Area of Science:

Neonatal care
Infectious disease prevention
Dermatology

Context:

Premature infants (<1kg, 7 months) require prolonged total parenteral nutrition (TPN).
Nosocomial infections pose a significant risk in this vulnerable population.
Optimizing skin antisepsis is vital during TPN to prevent infection.

Purpose:

To evaluate the biocide properties of various cutaneous antiseptics.
To identify agents with the best balance of efficacy and topical tolerability.
To inform antiseptic selection for premature neonates undergoing TPN.

Summary:

Reviews chloro-derivatives (sodium hypochlorite, NaDCC), alcohols (ethyl, propyl), chlorhexidine, and iodophors for cutaneous biocide properties.
Discusses triclosan and octenidine, noting their limited availability in Italy.
Highlights the importance of antiseptic choice for preventing nosocomial infections in low-birth-weight infants.

Impact:

Provides guidance on selecting appropriate skin antiseptics for high-risk neonates.
Aims to reduce the incidence of nosocomial infections in premature infants.
Contributes to improving patient safety and outcomes in neonatal intensive care units.