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Updated: May 24, 2026

Preparation of Mitochondria from Ovarian Cancer Tissues and Control Ovarian Tissues for Quantitative Proteomics Analysis

Preparation of Mitochondria from Ovarian Cancer Tissues and Control Ovarian Tissues for Quantitative Proteomics Analysis

Published on: November 18, 2019

Comparative mitochondrial proteomics: perspective in human diseases.

Yujie Jiang¹, Xin Wang

¹Department of Hematology, Provincial Hospital affiliated to Shandong University, Jinan, China.

Journal of Hematology & Oncology

|March 20, 2012

Summary

This summary is machine-generated.

Comparative mitochondrial proteomics reveals key cellular roles and disease associations. This research explores mitochondrial functions and dysfunctions, identifying potential therapeutic targets for human diseases.

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Last Updated: May 24, 2026

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Quantitative Analysis of Chromatin Proteomes in Disease

Quantitative Analysis of Chromatin Proteomes in Disease

Published on: December 28, 2012

Area of Science:

Cell Biology
Biochemistry
Proteomics

Background:

Mitochondria are vital organelles in eukaryotic cells, crucial for energy metabolism, apoptosis, and aging.
Mitochondrial dysfunction is implicated in numerous human diseases, making them a key research focus.

Purpose of the Study:

To review the advancements in comparative mitochondrial proteomics.
To explore the role of mitochondrial proteomics in understanding human diseases.

Main Methods:

Comparative proteomics allows comprehensive analysis of the mitochondrial proteome.
Techniques include 2D electrophoresis with mass spectrometry, ICAT, MudPIT, and SILAC.

Main Results:

Comparative proteomics offers insights into mitochondrial functions under various conditions.
Recent developments highlight applications in diverse human diseases.

Conclusions:

Mitochondrial proteomics enhances understanding of disease pathogenesis.
Identifies mitochondria as promising therapeutic targets for human diseases.