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Updated: May 24, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

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Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation

Ian W Glaaser1, Jeremiah D Osteen, Akil Puckerin

  • 1Department of Pharmacology, College of Physicians and Surgeons of Columbia University, Columbia University Medical Center, 630 W 168th Street, New York, NY 10032, USA.

Nature Communications
|March 20, 2012
PubMed

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