Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Assessment of Diffusion and Perfusion

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The AI Innerve Algorithm: Automatic Reproducible Reading for Intraepidermal Nerve Fiber Density Analysis, a New Tool for Small-Fiber Neuropathy Diagnosis.

European journal of neurology·2026

Same author

Transthyretin variant cerebral amyloid angiopathy fulfilling the modified Boston criteria: Retrospective data from the Bicêtre hospital cohort.

Revue neurologique·2025

Same author

Homozygous DNAJB4 deletion revealing myopathy with acute respiratory failure.

Revue neurologique·2025

Same author

Significant improvement of a nevus spilus-type congenital melanocytic nevus with oral selumetinib.

Pediatric dermatology·2024

Same author

Transthyretin amyloid polyneuropathy in France: A cross-sectional study with 413 patients and real-world tafamidis meglumine use (2009-2019).

Revue neurologique·2024

Same author

Tolerability of immune checkpoint inhibitors in patients with cancer and pre-existing multiple sclerosis.

European journal of cancer (Oxford, England : 1990)·2023

Search research articles

Related Experiment Video

Updated: May 24, 2026

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

Published on: August 26, 2014

Diffusion MRI and tensor tractography in ischemic optic neuropathy.

C Cauquil¹, R Souillard-Scemama, M Labetoulle

¹Department of Neurology, Centre Hospitalo-Universitaire de Bicêtre, Assistance Publique-Hôpitaux de Paris, 78 rue du Général Leclerc, 94275 Le Kremlin-Bicêtre Cedex, France.

Acta Neurologica Belgica

|March 20, 2012

Summary

Non-arteritic ischemic optic neuropathy (NAION) impacts vision, particularly in older adults. Advanced MRI techniques, including diffusion tensor tractography, show promise for diagnosing and assessing visual recovery in NAION cases.

More Related Videos

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

Related Experiment Videos

Last Updated: May 24, 2026

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

Published on: August 26, 2014

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

Area of Science:

Ophthalmology
Neurology
Radiology

Background:

Ischemic optic neuropathies (IONs) are a leading cause of vision loss in middle-aged and elderly populations.
While arteritic ION necessitates urgent corticosteroid treatment, non-arteritic ION (NAION) has limited therapeutic options.
Accurate diagnosis and assessment of visual prognosis in NAION are crucial.

Observation:

A case study of a woman with unilateral right-sided NAION is presented.
Clinical and radiographic findings were used for diagnosis.
Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps demonstrated restricted diffusion in the affected optic nerve, aiding in precise lesion localization.

Findings:

MRI, specifically DWI and ADC mapping, effectively identified the posterior optic nerve lesion in NAION.
Diffusion tensor tractography (DTT) emerged as a potentially objective method for evaluating incomplete visual recovery.
These advanced MRI techniques require further validation in larger patient cohorts.

Implications:

Advanced MRI techniques, including DTT, may offer new diagnostic and prognostic tools for NAION.
Further research in larger cohorts is needed to establish the role of these MRI techniques in clinical practice and therapeutic trials for ION.
Improved diagnostic and assessment methods could lead to better management strategies for NAION patients.