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Updated: May 24, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Primary breast lymphoma sequentially relapsed in the peripheral and central nervous system
Tzung-Chih Tang1, Hung Chang, Wen-Yu Chuang
1Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, No. 5, Fu-Shin Street, Linkou, Kweishan, Taoyuan 33305, Taiwan. tzungchih@gmail.com
Abstract:
Primary breast lymphoma (PBL) is an uncommon extranodal type of lymphoma, exhibiting more aggressive behavior and poorer prognosis. Patients with PBL have a higher incidence to relapse in central nervous system (CNS), which is always leading to a dismal outcome even treating with high intensity chemotherapy plus radiotherapy. Lymphoma involving the peripheral nervous system (PNS), either primarily or secondarily, is also rare. But no PBL with PNS relapse has been reported before. Herein, we reported a case of PBL who presented with subsequent relapse in two discrete sites of the PNS followed by the CNS.
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