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Updated: May 24, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Should magnesium be given to every migraineur? No
1Department of Neurology, Albert Szent-Györgyi Clinical Center, University of Szeged, Semmelweis u. 6, Szeged 6725, Hungary. apardutz@yahoo.com
Magnesium may help prevent migraine headaches, but evidence for its effectiveness in acute treatment is limited. While generally safe, it is not a universal solution for all migraineurs.
Area of Science:
- Neurology
- Neuroscience
- Pharmacology
Background:
- Migraine is a common neurological disorder causing significant disability and socio-economic impact.
- The exact pathophysiology of migraine remains incompletely understood, necessitating further research into effective therapies.
- Experimental studies suggest a role for magnesium ions in migraine pathophysiology.
Purpose of the Study:
- To evaluate the efficacy of magnesium in both prophylactic and acute migraine treatment.
- To assess the safety and potential niche applications of magnesium for migraine management.
Main Methods:
- Review of existing experimental studies and clinical data on magnesium's role in migraine.
- Analysis of evidence regarding magnesium's effectiveness in migraine prophylaxis versus acute therapy.
Main Results:
- Available data suggest magnesium has potential benefits for migraine prophylaxis.
- Evidence supporting magnesium's efficacy in acute migraine therapy is less convincing.
- Magnesium exhibits a favorable side effect profile, indicating relative safety.
Conclusions:
- Magnesium may be a beneficial adjunct therapy for migraine prophylaxis in certain patients.
- Current evidence does not support the universal use of magnesium for all migraineurs, especially given more effective treatment options.
- Further rigorous studies are needed to fully elucidate magnesium's role in migraine management.
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