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Evaluation of factors contributed in nonadherence to medication therapy in children asthma

Raheleh Mirsadraee1, Mohammad Gharagozlou, Masoud Movahedi

  • 1Department of Allergy and Clinical Immunology, Tehran University of Medical Sciences, Tehran, Iran.

Iranian Journal of Allergy, Asthma, and Immunology
|March 20, 2012
PubMed

Insights

Nonadherence to asthma medication in children is common, driven by concerns about costs, side effects like cardiac issues and drug dependency, and growth inhibition. Managing treatment complexity is key to improving adherence.

Area of Science:

  • Pediatric Pulmonology
  • Child Health
  • Pharmacological Adherence

Background:

  • Asthma is a prevalent chronic inflammatory condition in children.
  • Nonadherence to medical therapy significantly impacts pediatric asthma outcomes.
  • Identifying factors contributing to nonadherence is crucial for effective management.

Purpose of the Study:

  • To investigate the primary factors contributing to nonadherence in children with asthma.
  • To analyze the relationship between specific patient demographics, treatment regimens, and nonadherence.

Main Methods:

  • A descriptive study involving 150 children with asthma who were nonadherent to medication.
  • Data collected via self-report questionnaires detailing general information and reasons for nonadherence.
  • Statistical analysis to identify significant associations between variables.

Main Results:

  • Key nonadherence factors included concerns about drug dependency (38.7%), osteopenia (32%), and treatment expenses (34.7%).
  • Concerns about cardiac complications and drug dependency were inversely associated with multi-drug regimens.
  • Mild asthma severity was significantly linked to fear of drug dependency.

Conclusions:

  • Concerns regarding treatment expenses, potential side effects (cardiac, bone health, dependency), and growth inhibition are major drivers of nonadherence in pediatric asthma.
  • Complex treatment regimens, prolonged treatment duration, and polypharmacy prior to diagnosis are associated with higher nonadherence rates.
  • Addressing patient concerns and simplifying treatment plans are essential for improving medication adherence in children with asthma.

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