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Related Experiment Video

Updated: May 24, 2026

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study

Published on: August 15, 2016

Physicochemical perspective of cyclodextrin nano and microaggregates.

Pradipta Purkayastha¹, Syed S Jaffer, Prasun Ghosh

¹Department of Chemical Sciences, Indian Institute of Science Education and Research, Kolkata, Mohanpur 741252, WB, India. pradiptp@gmail.com

Physical Chemistry Chemical Physics : PCCP

|March 20, 2012

Summary

Supramolecular chemistry explores host-guest interactions using cyclodextrins. This study details cyclodextrin nanoaggregate formation, thermodynamics, and guest-induced morphology changes, primarily via spectroscopy.

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Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

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Published on: August 2, 2012

Area of Science:

Supramolecular Chemistry
Host-Guest Chemistry
Physical Chemistry

Background:

Supramolecular chemistry, or "chemistry beyond the molecule," relies on molecular recognition.
Cyclodextrins are prominent hosts due to their solubilization and biocompatibility.
Host-guest chemistry is central to supramolecular studies.

Purpose of the Study:

Revisit host-guest aspects of cyclodextrins from a physicochemical viewpoint.
Detail cyclodextrin nanoaggregate formation and applications induced by guest molecules.
Analyze thermodynamics and guest concentration effects on aggregate morphology.

Main Methods:

Spectroscopic analysis provides key insights.
Investigating guest-induced cyclodextrin nanoaggregate formation.
Thermodynamic analysis of host-guest interactions.

Main Results:

Cyclodextrin nanoaggregate formation is guest-molecule dependent.
Thermodynamics govern the self-assembly process.
Guest concentration influences aggregate morphology.

Conclusions:

Cyclodextrins are versatile hosts for supramolecular applications.
Physicochemical properties dictate nanoaggregate behavior.
Spectroscopic methods are crucial for understanding these systems.