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Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
Published on: August 25, 2019
[Predicting pregnancy outcomes based on first trimester screening]
1Ultrasound Unit, Obstetrics and Gynecology Department, Meir Medical Center, Kfar-Saba, affilated to the Sackler Faculty of Medicine, Tel Aviv University. rami.aviram@clalit.org.il
Abstract:
Pregnancy surveillance in the western world focuses on the second and third trimesters. Recently, a few studies demonstrated that several pregnancy outcomes can be predicated by first trimester screening, especially in the time period between 11 + 0 to 13 + 6 weeks of gestation. These outcomes include the risk of developing preeclampsia, small for gestational age (SGA) and macrosomic fetuses, risk of abortion or intrauterine fetal death, risk of preterm labor and the risk of developing gestational diabetes. This review focuses on these findings and examines if it is feasible to expand the nuchal translucency and first trimester biochemical screening that is customary in Israel, so it may include additional parameters to predict those pregnancy outcomes.

