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Two new sesquiterpene lactones from the supercritical fluid extract of Centipeda minima
Peng Wu1, Xiao-Guang Li, Ning Liang
1Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China.
Journal of Asian Natural Products Research
|March 21, 2012
Abstract:
Two new sesquiterpene lactones, minimolides G(1) and H(2), were isolated from the supercritical fluid extract of Centipeda minima. Their structures were elucidated on the basis of extensive analyses of spectroscopic data including IR, HR-ESI-MS, 1D and 2D NMR. Compounds 1 and 2 displayed inhibitory activity against human nasopharyngeal cancer cell line (CNE) with IC₅₀ values of 61.4 and 28.7 μM, respectively.
