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Erythromelalgia.

A L Mehle1, S Nedorost, C Camisa

  • 1Department of Dermatology, Cleveland Clinic, Foundation, Ohio 44195-5032.

International Journal of Dermatology
|October 1, 1990
PubMed
Summary
This summary is machine-generated.

Erythromelalgia, a condition causing burning pain and redness, can be linked to essential thrombocythemia or pernicious anemia. This study presents two cases, highlighting these important associations for better diagnosis.

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Area of Science:

  • Hematology
  • Dermatology
  • Internal Medicine

Background:

  • Erythromelalgia presents as a distinct syndrome of temperature-dependent extremity redness, pain, and warmth.
  • It can manifest as a primary condition or secondary to other systemic diseases.
  • Known associations include myeloproliferative disorders like essential thrombocythemia.

Observation:

  • This report details two distinct cases of erythromelalgia.
  • One case involved a patient with essential thrombocythemia.
  • The second case describes the first reported instance of erythromelalgia associated with pernicious anemia.

Findings:

  • The study confirms the association between erythromelalgia and essential thrombocythemia.
  • It establishes a novel association between erythromelalgia and pernicious anemia.

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  • These findings expand the known spectrum of secondary causes for erythromelalgia.

    • Implications:

    • Recognizing these associations can aid in the timely diagnosis of underlying conditions.
    • This research may prompt further investigation into the pathophysiology linking these disorders.
    • Clinicians should consider screening for essential thrombocythemia and pernicious anemia in patients with erythromelalgia.