Related Experiment Video
Updated: May 23, 2026
Electroantennographic Bioassay as a Screening Tool for Host Plant Volatiles
Published on: May 6, 2012
Susceptibility testing of Atopobium vaginae for dequalinium chloride
Guido Lopes dos Santos Santiago1, Philipp Grob, Hans Verstraelen
1Laboratory Bacteriology Research, Faculty Medicine & Health Sciences, University of Ghent, Ghent, Belgium. guido.lopesdossantossantiago@ugent.be
Background:
Atopobium vaginae and Gardnerella vaginalis are major markers for bacterial vaginosis. We aimed to determine the MIC and MBC range of the broad-spectrum anti-infective and antiseptic dequalinium chloride for 28 strains, belonging to 4 species of the genus Atopobium, i.e. A. vaginae, A. minutum, A. rimae and A. parvulum.
Methods:
The MIC was determined with a broth microdilution assay.
Results:
The MIC and MBC for Atopobium spp. for dequalinium chloride ranged between < 0.0625 and 2 μg/ml.
Conclusions:
This study demonstrated that dequalinium chloride inhibits and kills clinical isolates of A. vaginae at concentrations similar to those of clindamycin and lower than those of metronidazole.
