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Rapid Collection of Floral Fragrance Volatiles using a Headspace Volatile Collection Technique for GC-MS Thermal Desorption Sampling
Published on: December 10, 2019
Fragrance material review on isojasmone
J Scognamiglio1, L Jones, C S Letizia
1Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA. jscognamiglio@rifm.org
Summary
This review examines isojasmone, a fragrance ingredient, detailing its toxicologic and dermatologic safety data. It confirms isojasmone
Area of Science:
- Toxicology
- Dermatology
- Fragrance Chemistry
Background:
- Isojasmone belongs to the ketone fragrance group, specifically cyclopentanones and cyclopentenones.
- These compounds share a core cyclopentanone or cyclopentenone ring structure with alkyl or alkenyl substituents.
Purpose of the Study:
- To present a comprehensive toxicologic and dermatologic review of isojasmone as a fragrance ingredient.
- To summarize available data on isojasmone's physical properties, acute toxicity, and irritation potential.
Main Methods:
- Literature review and data compilation on isojasmone.
- Evaluation of toxicology and dermatology studies related to the ingredient.
- Summarization of physical properties, acute toxicity, skin and eye irritation, and skin sensitization data.
Main Results:
- Compilation of physical properties for isojasmone.
- Summary of acute toxicity, skin irritation, eye irritation, and skin sensitization data.
- Isojasmone data is part of a larger safety assessment for ketones, cyclopentanones, and cyclopentenones.
Conclusions:
- Isojasmone data has been evaluated and summarized.
- This review is intended to supplement a broader safety assessment of related fragrance ingredients.
- Refer to Belsito et al. (2012) for the overall safety assessment of isojasmone and related compounds.
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