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Published on: November 6, 2019
Systematic review of randomized controlled trials comparing intracapsular tonsillectomy with total tonsillectomy in a
Joanna Walton1, Yaniv Ebner, Michael G Stewart
1Department of Otolaryngology, Addenbrooke's Hospital, Cambridge, England.
Insights
Intracapsular tonsillectomy (IT) offers better recovery than total tonsillectomy (TT) in children with obstructive symptoms. Patients experience less pain and a lower rate of secondary hemorrhage with IT, supported by level-1 evidence.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Evidence-Based Medicine
Background:
- Tonsillectomy is a common pediatric surgical procedure.
- Debate exists regarding optimal tonsillectomy technique, specifically intracapsular (IT) versus total (TT).
- Level-1 evidence comparing recovery outcomes is limited.
Purpose of the Study:
- To systematically review and synthesize level-1 evidence comparing recovery outcomes between IT and TT in pediatric patients.
- To evaluate differences in postoperative pain, analgesic use, recovery time, diet, bleeding, infection, and tonsil regrowth.
Main Methods:
- Systematic literature review of randomized controlled trials (RCTs) in pediatric populations.
- Searched multiple databases including MEDLINE and Web of Science.
- Two independent reviewers selected studies, with disagreements resolved by a third reviewer.
Main Results:
- Formal meta-analysis was precluded by heterogeneity and lack of raw data.
- Pooled data analysis using nonparametric tests was performed where possible.
- Intracapsular tonsillectomy demonstrated superior recovery-related outcomes compared to total tonsillectomy.
Conclusions:
- Intracapsular tonsillectomy is associated with improved recovery, including reduced secondary hemorrhage and faster pain resolution, in pediatric patients with obstructive symptoms.
- Level-1 evidence supports IT as a favorable alternative to TT for specific patient groups.
- Further standardization of outcome reporting in RCTs is recommended.
Objective:
To perform a systematic literature review and data synthesis of level-1 evidence comparing recovery-related outcomes after intracapsular tonsillectomy (IT) (any technique) with those of total tonsillectomy (TT) (any technique) in a pediatric population.
Data Sources:
Two independent reviewers searched the following databases: Ovid MEDLINE, including old MEDLINE and pre-MEDLINE, EBM reviews, Books@Ovid and Journals@Ovid, the Web of Science with Conference Proceedings, and references from indexed articles.
Study Selection:
Inclusion criteria were randomized controlled trials conducted on a pediatric population comparing IT performed by any technique of dissection with TT, also performed by any technique of dissection. Two independent reviewers determined included trials with difference of opinion resolved by a third reviewer.
Data Extraction:
Independent data extraction by 2 reviewers on the following outcomes: postoperative pain, analgesic use, recovery time, diet, bleeding rate, infection, and regrowth rate requiring further surgical intervention.
Data Synthesis:
Heterogeneity of outcome measures and lack of reporting of raw data precluded formal meta-analysis. For quantitative data that could be extracted, pooled data analysis was performed using nonparametric tests.
Conclusion:
Recovery-related outcomes for IT were superior to TT (secondary hemorrhage rate, number of days until pain free) in a pediatric population with obstructive symptoms (level-1 evidence).
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