Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sensory-selective Sciatic Nerve Block with 2',6' Pipecolylxylidine in an Ovine Model.

Anesthesiology·2026
Same author

Sensory-selective Peripheral and Neuraxial Nerve Blockade with 2',6'-Pipecoloxylidide: Erratum.

Anesthesiology·2026
Same author

Polymeric rapamycin nanoparticles encapsulating ponatinib cause regression of venous malformations in mice.

Science translational medicine·2026
Same author

Polyketal-conjugated tafluprost microparticles enable long-acting glaucoma therapy.

Nature communications·2026
Same author

Extruded droplet-on-demand (X-DoD) bioprinting for controlled iPSC-based functional cortical network formation.

Biofabrication·2026
Same author

Precise Spatiotemporal Control of Sensory Nerve Blockade via Light-Triggered Click-Release Uncaging of 2',6'-Pipecoloxylidide.

Angewandte Chemie (International ed. in English)·2026

Related Experiment Video

Updated: May 23, 2026

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets
09:24

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Published on: October 3, 2014

Delivering bioactive molecules as instructive cues to engineered tissues.

Doris Gabriel1, Tal Dvir, Daniel S Kohane

  • 1Children's Hospital Boston, Harvard Medical School, Division of Critical Care Medicine, Department of Anesthesiology, Laboratory for Biomaterials and Drug Delivery, 300 Longwood Avenue, Boston, MA 02115, USA.

Expert Opinion on Drug Delivery
|March 22, 2012
PubMed
Summary
This summary is machine-generated.

Bioactive molecules, like growth factors, are essential for tissue engineering. Advanced drug delivery systems enable sustained release, improving engineered tissue function and development.

More Related Videos

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
10:14

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells

Published on: November 18, 2016

Related Experiment Videos

Last Updated: May 23, 2026

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets
09:24

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Published on: October 3, 2014

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
10:14

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells

Published on: November 18, 2016

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Drug Delivery

Background:

  • Bioactive molecules, including growth factors, are critical for developing functional engineered tissues from cells.
  • Delivery of these molecules influences cellular behavior within engineered constructs.

Purpose of the Study:

  • To review the delivery of bioactive molecules, especially growth factors, for modulating cell function in tissue engineering.
  • To explore biological targets, molecule types, scaffold materials, and delivery strategies.

Main Methods:

  • Review of literature on bioactive molecule delivery in tissue engineering.
  • Discussion of scaffold materials and drug delivery systems.
  • Analysis of various drug delivery strategies for controlled release.

Main Results:

  • Drug delivery systems facilitate sustained release of bioactives, significantly enhancing engineered tissue function.
  • Advanced techniques allow for precise control over the timing and location of bioactive molecule release.

Conclusions:

  • Sustained and patterned release of bioactives can recapitulate developmental processes in engineered tissues.
  • Future advancements in drug delivery, materials, and molecular discoveries will further impact the field.