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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...

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Related Experiment Video

Updated: May 23, 2026

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration
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Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration

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Resveratrol: potential as anticancer agent.

Julia Khristine Aluyen1, Quynhanh N Ton, Thuytram Tran

  • 1Feik School of Pharmacy, University of the Incarnate Word, San Antonio, Texas 78209, USA.

Journal of Dietary Supplements
|March 22, 2012
PubMed
Summary
This summary is machine-generated.

Resveratrol shows promise as an anticancer agent by inhibiting cancer cell growth and promoting apoptosis. Further human studies are needed to confirm its effectiveness and optimal dosage for cancer prevention.

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Last Updated: May 23, 2026

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Published on: June 26, 2018

Area of Science:

  • Natural product chemistry
  • Pharmacology
  • Oncology

Background:

  • Cancer remains a leading global cause of mortality, driving the search for less toxic, effective treatments.
  • Resveratrol (3,5,4'-trihydroxystilbene), a natural compound from red wine and grapes, is investigated for its chemopreventive properties.
  • Resveratrol's potential anticancer mechanisms include inducing apoptosis, inhibiting proliferation, and reducing inflammation.

Purpose of the Study:

  • To systematically review the evidence on resveratrol's efficacy as an anticancer agent.
  • To evaluate the documented mechanisms of action for resveratrol in cancer chemoprevention.

Main Methods:

  • A systematic review of primary, secondary, and tertiary references was conducted.
  • Databases searched included PubMed, EBSCO, Cochrane, AccessPharmacy, and StatRef.
  • Search terms were "resveratrol," "cancer," and "anticancer," focusing on animal and human studies within the last 10 years.

Main Results:

  • Resveratrol exhibits anticancer effects through proapoptotic, antiproliferative, and anti-inflammatory actions.
  • In vitro and in vivo studies support these anticancer mechanisms, suggesting the need for human trials.
  • Human pharmacokinetic studies indicate good tolerability but low absorption rates.

Conclusions:

  • Resveratrol demonstrates potential anticancer properties.
  • Its chemopreventive effects appear to be dose- and duration-dependent.
  • Resveratrol may have synergistic effects with conventional anticancer drugs, warranting further clinical investigation.