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Folate status assessment.

L B Bailey1

  • 1Food Science and Human Nutrition Department, University of Florida, Gainesville 32611.

The Journal of Nutrition
|November 1, 1990
PubMed
Summary
This summary is machine-generated.

Assessing folate status involves measuring serum and red blood cell folate levels. Factors like alcohol, smoking, and life stages such as pregnancy impact folate needs and utilization.

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Area of Science:

  • Biochemistry
  • Nutritional Science
  • Hematology

Background:

  • Folate is essential for DNA synthesis and cell division.
  • Folate deficiency can lead to serious health issues.
  • Understanding folate status assessment and risk factors is crucial for public health.

Purpose of the Study:

  • To review established methods for assessing folate status.
  • To identify key factors influencing folate status and deficiency risk.
  • To highlight folate status considerations across the human life cycle.

Main Methods:

  • Review of established methods for folate status assessment.
  • Analysis of factors affecting folate utilization and requirements.
  • Examination of physiological and lifestyle influences on folate levels.

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Main Results:

  • Serum and red blood cell folate levels indicate early depletion.
  • The deoxyuridine suppression test assesses functional folate status.
  • Erythrocyte morphology and hemoglobin concentration reflect impaired cell division.
  • Alcohol, smoking, drugs, pregnancy, lactation, adolescence, and senescence affect folate status.

Conclusions:

  • Folate status assessment requires a multi-faceted approach.
  • Dietary intake, utilization, and increased requirements influence folate status.
  • Specific life stages and lifestyle factors necessitate careful monitoring of folate levels.